CGRP (83-119), rat TFA

Research use only, not for human use.

Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.

Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.(In Vitro):Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) belongs to the calcitonin family of neuropeptides which also includes adrenomedullin, amylin, calcitonin, intermedin and calcitonin receptor-stimulating peptide. Calcitonin Gene Related Peptide (CGRP) has two isoforms (αCGRP and βCGRP), and acts through calcitonin receptor-like receptor (CRLR). Calcitonin Gene Related Peptide (CGRP) plays a key role in migraine pathophysiology and is associated with activation of the trigeminovascular system. CGRP prossibly acts postjunctionally in these areas putatively involved in primary headaches.(In Vivo):Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) is a potent inducer of oedema in rat orofacial tissue. CGRP (100 μL; 8-33 pM) induces a rapidly developing (5-15?min) and long-lasting (6?h), dose-dependent oedema in the rat cheek. CGRP induces a smaller oedematogenic effect in the rat hind paw also blocked by the CGRP antagonist. CGRP (16 pM) potentiates the oedema induced by co-injected substance P (3.7 nM).

——

——

Calcitonin Gene Related Peptide(83-119), rat TFA

Others

Other Targets

——

——

——

——

3920.32

C162H262N50O52S2.C2HF3O2

>98% (HPLC)

H2O : 10 mg/mL (2.55 mM; Need ultrasonic)

——

Sequence:Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2 (Disulfide bridge: Cys2-Cys7)

(-20℃)

With Ice Pack

≥ 2 years